The perinatal period and toxic risks (PERITOX)

Contact name	Email	phone number
BACH Véronique	veronique.bach@u-picardie.fr
BOYELDIEU Emmanuelle	emmanuelle.boyeldieu@u-picardie.fr	03 22 82 78 96
CHARDON Karen	karen.chardon@u-picardie.fr
BROCHOT Céline	celine.BROCHOT@ineris.fr

https://peritox.u-picardie.fr/

Avenue René Laënnec

80054 Amiens Cedex 1

• Impact of perinatal exposure to toxic environmental factors (pesticides) or physical factors (mobile telephony radiofrequencies, and thermal stress) on child health (sleep, thermoregulation, breathing, digestion, etc.). • We study newborns, in vitro systems and in silico models in a complementary, coherent way. • Risk exposure analysis • Molecular & cell biology • Integrated physiology, • Use of innovative, stress- and/ or contact-free tools suited to the newborn’s body size and models that avoid unnecessary animal or human experiments (e.g. an artificial intestine and a thermal mannequin).

Nombre de chercheurs : 36
Nombre de doctorants :
Nombre de personnel d'appui à la recherche : 8
Effectif total : 56

1. GOLIAT 5G project expOsure, causaL effects, and rIsk perception through citizen engAgement European project funded under the call "Exposure to electromagnetic fields (EMF) and health (HORIZON-HLTH-2021-ENVHLTH-02-01) Budget: 8M€ 21 partners from 12 countries. 2. HBM4EU Project: European Human Biomonitoring Initiative H2020 SOCIETAL CHALLENGES - Health, demographic change and well-being (2017-2022) Budget: €75m. Partners: 26 countries, approximately 130 partners. 3. ANSES PNR-EST "EXSOCAR" project: Study of the effects of 5G exposure on sleep, thermoregulation and cardiovascular function. National Environment, Health and Work Research Program (ENR EST) Radio Frequency and Health 2021-2024 Project Budget: 200 k(E). Partners: PériTox (holder), PlatAnn Platform (UPJV), Stéphane Tanguy (Equipe Preta, University of Grenoble), Giovanna Zoccoli (PRISM Team, University of Bologna). 4. ANSES PNR-EST “NeuroPrem-RF” project: “Impact of chronic exposure to radio-frequency electro-magnetic fields on the neurophysiological development of premature newborns”. National Environment, Health and Work Research Program (ENR EST) Radio Frequency and Health Research Project - 2018-2021 Budget: €248 K; Partners: PériTox (holder), CHU Amiens-Picardie. 5. NEUROPHYTO Project; Neurodevelopmental Effects Assessment of Prenatal and Postnatal Exposure to Plant Protection Products ECOPHYTO APR project "Plant protection products: from exposure to impacts on human health and ecosystems" (2020 - 2023) Budget €400k. Partners: Ineris (holder); Luxembourg Institute of Health; IRSET-INSERM; UDP-INSERM 6. ThermoK4Preterm Interregional PHRC Project: Premature Babies in Incubators: Automated Heat Control in a Randomized Trial – Improved Weight Growth and Reduced Morbidity. Demonstration of the benefit in the premature of the use of an incubator tuning software, «PRETHERM», developed by the team in a previous project funded by the National Research Agency (ANR). Interregional Clinical Research Hospital Program Budget: €281 K; Partners: PériTox (holder), CHU Amiens-Picardie and 5 other regional hospital structures.

1. Comment on "metformin-related lactic acidosis with acute kidney injury: results of a French observational multicenter study". Lalau JD, Bennis Y, De Broe M.Clin Toxicol (Phila). 2019 Dec 2:1. 🡭 2. Determination of maternal and foetal distribution of cis- and trans-permethrin isomers and their metabolites in pregnant rats by liquid chromatography tandem mass spectrometry (LC-MS/MS). Personne S, Marcelo P, Pilard S, Baltora-Rosset S, Corona A, Robidel F, Lecomte A, Brochot C, Bach V, Zeman F. Anal Bioanal Chem. 2019 Dec. 🡭 3. Environmental radiofrequency electromagnetic field levels in a department of pediatrics. Besset D, Selmaoui B, Tourneux P, Leke A, Delanaud S, de Seze R, Stephan Blanchard E.. Environ Res. 2019 Nov 6. 🡭 4. Real-world evidence of tofacitinib effectiveness and safety in patients with refractory ulcerative colitis. Lair-Mehiri L, Stefanescu C, Vaysse T, Laharie D, Roblin X, Rosa I, Treton X, Abitbol V, Amiot A, Bouguen G, Dib N, Fumery M, Pariente B, Carbonnel F, Peyrin-Biroulet L, Simon M, Viennot S, Bouhnik Y. Dig Liver Dis. 2019 Nov 12. 🡭 5. Effects of co-exposure to 900 MHz radiofrequency electromagnetic fields and high-level noise on sleep, weight, and food intake parameters in juvenile rats. Bosquillon de Jenlis A, Del Vecchio F, Delanaud S, Bach V, Pelletier A. Environ Pollut. 2020 Jan.. 🡭 All publications can be found here : 🡭

National : Artois ULCO France, Université de Grenoble, France. International : Western australia university Perth Australie , Monash university Hudson institute of medical research Melbourne Australie, Université de Bologne Italie.

Médipréma, Décathlon, Terre de Marins, Sebac

Training of the Institute of Health Engineering (2IS, UFR de Médecine, UPJV) in particular in the "Management of Health, Safety and Environment at Work" sector, as well as in the "Health, Safety and Environment" IUT (Creil, UPJV). Toxicology Training (Ineris Formation).

We provide services according to our expertise (Thermal, Electro-Magnetic Fields).

We provide consulting services according to our expertise.

• University of Picardie Jules Verne (UPJV)

• Health and Nutrition
• Chemistry and Materials
• Food ingredients
• New therapeutic approaches
• Medicine of the future: new health equipment and e-health
• Organic chemistry