• Health and Nutrition

Magnetic Resonance Imaging Platform for Small Animals (PIRMPA)

Platform

Description

The platform is mainly dedicated to in vivo magnetic resonance imaging (MRI) and spectrometry (MRS) of small animals, but also of any sample containing hydrogen. It proposes different techniques that allow morphological exploration by the main families of sequences:

• T1 or T2 weighted imaging (longitudinal or transverse relaxation time) or DP (proton density)
• Vessel time of flight (or phase contrast) angiography
• With or without injection of gadolinium chelate contrast agent (tumor)

But also functional exploration:

• Hemodynamic imaging of brain activity
• Microvascular (perfusion)
• Metabolic (1H spectroscopy)
• Tissue microstructure (diffusion, tractography)
• Flow (blood flow and volume)

The platform can support its users in designing their image acquisition protocols, processing and data analysis. In compliance with the regulations of animal transport, the MRI platform is connected to the CURS pet store (PlatanN) which has solutions for housing your animals, in respect of animal welfare.

Contacts

  • Olivier BALEDENT
    Manager
  • Sidy FALL
    Manager

Informations

30 Avenue de la croix Jourdain
Centre Universitaire de Recherche en Santé (CURS) CHU Amiens-Picardie
80000 AMIENS

https://www.u-picardie.fr/plateformes/pirmpa/

Expertises

Skills

• T1 or T2 weighted imaging (longitudinal or transverse relaxation time) or DP (proton density)
• Vessel time of flight (or phase contrast) angiography
• With or without injection of gadolinium chelate contrast agent (tumor)
• Hemodynamic imaging of brain activity
• Microvascular (perfusion)
• Metabolic (1H spectroscopy)
• Tissue microstructure (diffusion, tractography)
• Flow (blood flow and volume)

Example(s) of projects

Neurobiological mechanisms involved in schizophrenia-addiction co-morbidity: longitudinal and multimodal structural and functional MRI analysis; severe acute alcoholic hepatitis model in mice and intestinal microbiota transplantation.

Collaborations/Partners/Private Clients

BRUKER

Services offers

Consulting services

Consulting services according to our expertise

Equipments

The main equipment of the platform is a 7 tesla horizontal imager (Bruker, BioSpec 70/20 USR, Avance NEO Spectrometer), with a magnetic field gradient ring of 440 mT/m with an internal diameter of 70 mm. It also has a wide range of volume and surface coils (head and whole body for small animals), a gaseous anaesthesia station, a module for real-time monitoring of physiological parameters (heart rate, respiratory rate and body temperature) as well as heating blankets for maintaining the body temperature of animals under anaesthesia.

Equipments

Nom Modèle Marque
300 Mhz Horizontal Imager (BioSpec, 7T) 70/20 USR / BRUKER
Spectrometer Système d'électronique: AVANCE NEO/ BRUKER
Range of surface and volume antennas (probes) BRUKER
Acquisition, reconstruction and data processing consoles ParaVision 360 / Bruker
Anesthesia Station and Monitoring Module TemSega - SA.Instruments

Ecosystem

Affiliated institutions / organisations

University of Picardie Jules Verne

Partner institution(s)

Regional strategic areas of activity

  • Health and Nutrition
    • Medicine of the future: new health equipment and e-health
    • New therapeutic approaches

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Thematics

Current thematics

  • Health and Nutrition
    • Medicine of the future: new health equipment and e-health
    • New therapeutic approaches
Title

Current content

Magnetic Resonance Imaging Platform for Small Animals
Type

Current content

Plateforme analytique
Description

Current content

The platform is mainly dedicated to in vivo magnetic resonance imaging (MRI) and spectrometry (MRS) of small animals, but also of any sample containing hydrogen. It proposes different techniques that allow morphological exploration by the main families of sequences:

• T1 or T2 weighted imaging (longitudinal or transverse relaxation time) or DP (proton density)
• Vessel time of flight (or phase contrast) angiography
• With or without injection of gadolinium chelate contrast agent (tumor)

But also functional exploration:

• Hemodynamic imaging of brain activity
• Microvascular (perfusion)
• Metabolic (1H spectroscopy)
• Tissue microstructure (diffusion, tractography)
• Flow (blood flow and volume)

The platform can support its users in designing their image acquisition protocols, processing and data analysis. In compliance with the regulations of animal transport, the MRI platform is connected to the CURS pet store (PlatanN) which has solutions for housing your animals, in respect of animal welfare.
Contact informations
Contact

Current content

Contact name Email phone number
BALEDENT Olivier olivier.baledent@u-picardie.fr (+33) 6 67 98 20 41
FALL Sidy sidy.fall@u-picardie.fr (+33)3 22 82 53 59
URL

Current content

https://www.u-picardie.fr/plateformes/pirmpa/

Address

Current content

30 Avenue de la croix Jourdain
Centre Universitaire de Recherche en Santé (CURS) CHU Amiens-Picardie
80000 AMIENS
Keywords

Current content

In vivo/ in vitro imaging, Magnetic resonance, MRI, Spectroscopy, Preclinical imaging, Tractography, Blood flow, Brain, Cardiovascular, Hepatic.
Our search domains
Skills

Current content

• T1 or T2 weighted imaging (longitudinal or transverse relaxation time) or DP (proton density) • Vessel time of flight (or phase contrast) angiography • With or without injection of gadolinium chelate contrast agent (tumor) • Hemodynamic imaging of brain activity • Microvascular (perfusion) • Metabolic (1H spectroscopy) • Tissue microstructure (diffusion, tractography) • Flow (blood flow and volume)
Key data

Current content

Workforce

Current content

Effectif total :
Example(s) of projects

Current content

Neurobiological mechanisms involved in schizophrenia-addiction co-morbidity: longitudinal and multimodal structural and functional MRI analysis; severe acute alcoholic hepatitis model in mice and intestinal microbiota transplantation.
Example(s) of publications

Current content

Collaborations/Partners/Scientific clients

Current content

Collaborations/Partners/Private Clients

Current content

BRUKER
Services offers
Training offers

Current content

Services offers

Current content

Consulting services

Current content

Consulting services according to our expertise
Equipments
Equipements spécifiques

Current content

  • 300 Mhz Horizontal Imager (BioSpec, 7T)
    70/20 USR / BRUKER
  • Spectrometer
    Système d'électronique: AVANCE NEO/ BRUKER
  • Range of surface and volume antennas (probes)
    BRUKER
  • Acquisition, reconstruction and data processing consoles
    ParaVision 360 / Bruker
  • Anesthesia Station and Monitoring Module
    TemSega - SA.Instruments
Ecosystem
Affiliated institutions / organisations

Current content

  • University of Picardie Jules Verne
Établissement(s) partenaire(s)

Current content

Unit(s) of attachment

Current content

Groups/Networks/Federations

Current content

Competitive cluster

Current content

Regional strategic areas of activity

Current content

  • Health and Nutrition
  • New therapeutic approaches
  • Medicine of the future: new health equipment and e-health
Labelling

Current content

Personal informations
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