• Bioeconomy
  • Chemistry and Materials

Enzymatic and Cellular Engineering (GEC)

Research unit - UMR-CNRS 7025

Description

The research conducted within the GEC is based on the premise that solutions to major scientific challenges are found in nature. They combine three approaches: the use of bioresources, bioinspiration and biomimicry.
With its internationally recognized expertise in biotechnology, the GEC unit develops various models of varying levels of complexity, to explain the dynamics of biological phenomena and to propose innovative solutions to scientific and societal problems.
The activities of the GEC are thus naturally linked between the exploitation of bioresources and plant metabolism and the creation of bioinspired materials or molecular mimes for recognition.

Contacts

  • Karsten Haupt
    Director

Informations

Rue du docteur Schweitzer
60200 COMPIEGNE

http://www.umr7025-gec.fr/

Effectif

Effectif total : 37

Personnel de recherche : 24

Personnel d'appui à la recherche : 13

Expertises

Skills

• Biotechnology
• Biomimetics
• Plant metabolism
• Biolubricants
• Biofuels
• Antioxidants
• Anticancer
• Antimicrobials
• Antifungals
• Antibiotic resistance
• Study of pathogenic host relationship mechanisms

Example(s) of projects

• FuturoLeaf: develops a bio-inspired SSCF technology based on the hierarchical and porous 3D assemblies of nanocellulosic materials capturing water and transporting gases and nutrients for the photosynthetic microbial cells
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• SAMOSS: Improving the development of biosensors in combination with optochemical detection techniques in application areas and through wider dissemination of knowledge

• EraDic: Develop a predictive tool for recurrence in patients with chronic myeloid leukemia after cessation of conventional treatment with first- and second-generation kinase inhibitors

• COALA: elucidate the antifungal mode of action of amphiphilic lipid compounds on rapeseed pathogens.

• XYLESA: isolate specific peptide ligands of lipase secreted in the establishment of diseases associated with Xylella fastidiosa, capable of recognizing it for diagnostic applications and inhibiting its enzymatic activity for phytosanitary applications.

• ANOI aims to determine the identification and classification of oilseed plants of interest and to improve the productivity of oilseed crops of four model plants.

Example(s) of publications

1. Raquel Martins-Noguerol, Sebastien Acket, Manuel Adrián Troncoso-Ponce, Rafael Garcés, Mónica Venegas-Calerón et al. Characterization and impact of sunflower plastidial octanoyltransferases (Helianthus annuus L.) on oil composition
Journal of Plant Physiology, Elsevier, 2022, 274, pp.153730. 🡭

2. Sivanandam Veeramuthu Natarajan, Nicola D’amelio, Victor Muñoz. NMR Relaxation Dispersion Methods for the Structural and Dynamic Analysis of Quickly Interconverting, Low-Populated Conformational Substates Protein Folding, 2376, Springer US, pp.187-203, 2022, Methods in Molecular Biology, 🡭

3.Thomas Verissimo, Anna Faivre, Anna Rinaldi, Maja Lindenmeyer, Vasiliki Delitsikou et al. Decreased Renal Gluconeogenesis Is a Hallmark of Chronic Kidney Disease
Journal of the American Society of Nephrology, American Society of Nephrology, 2022, 🡭

4. Juan Carlos Rubio-Gutierrez, Pablo Mendez-Hernández, yann Guéguen, Pierre Galichon, Marcela Tamayo-Ortiz et al. Overview of Traditional and Environmental Factors Related to Bone Health Environmental Science and Pollution Research, Springer Verlag. 🡭

5. Nébéwia Griffete, Laurent Michot, Carlo Gonzato. An easy synthesis of small, stable and water-compatible superparamagnetic protein-specific molecularly imprinted nanoparticles Polymer, Elsevier, 2022, 239, pp.124446. 🡭


All our publications can be found here : 🡭

Collaborations/Partners/Scientific clients

Université Picardie Jules Verne, Sorbonne Université, INSERM, Université de Paris, Université de Reims Champagne-Ardenne, Institut Pasteur, Russian Academy Of Scinces, Université de Lille, Université de Laval, VTT Technical Research Centre of Finland Ltd

Collaborations/Partners/Private Clients

EXTRACTIS, SAS PIVERT, SAS IMPROVE, OLEON, SANOFI, L'OREAL

Services offers

Applications sectors

  • Biotechnology
  • Health / wellness
  • Agriculture
  • Education / Training
  • Cosmetics
  • Science / Research

Services provided

We provide services on all our skills

Training offers

We provide training on all our skills

Consulting services

We provide consulting services on all our skills

Equipments

Biocatalysis, implementation of enzymes in unconventional environments: reactors, identification and quantification, kinetic monitoring, HPLC fleet.


Biophysical characterization of biomolecules, self-assembly of amphiphilic molecules, biomimetic membranes: liquid and solid NMR, Diffusion of laser beam, molecular dynamics simulations, peptide webserver.


Fermentation: batch and reactors


Discover the detailed equipment list: 🡭

Ecosystem

Affiliated institutions / organisations

CNRS
Université de Technologie de Compiègne (UTC)

Regional strategic areas of activity

  • Bioeconomy
    • Biobased chemistry
    • Processes applied to the bioeconomy
  • Chemistry and Materials
    • Industrial processes engineering, efficient processes
    • Recycling of materials and efficient use of material resources
    • Textiles, composites, materials

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Thematics

Current thematics

  • Bioeconomy
    • Biobased chemistry
    • Processes applied to the bioeconomy
  • Chemistry and Materials
    • Industrial processes engineering, efficient processes
    • Recycling of materials and efficient use of material resources
    • Textiles, composites, materials
Title

Current content

Enzymatic and Cellular Engineering
Type

Current content

Research unit
Description

Current content

The research conducted within the GEC is based on the premise that solutions to major scientific challenges are found in nature. They combine three approaches: the use of bioresources, bioinspiration and biomimicry.
With its internationally recognized expertise in biotechnology, the GEC unit develops various models of varying levels of complexity, to explain the dynamics of biological phenomena and to propose innovative solutions to scientific and societal problems.
The activities of the GEC are thus naturally linked between the exploitation of bioresources and plant metabolism and the creation of bioinspired materials or molecular mimes for recognition.
Contact informations
Contact

Current content

Contact name Email phone number
HAUPT Karsten karsten.haupt@utc.fr
URL

Current content

http://www.umr7025-gec.fr/

Address

Current content

Rue du docteur Schweitzer

60200 COMPIEGNE
Keywords

Current content

Plant metabolism, Biomimetics, Molecular diversity, Plant valorisation, Biocontrol, Biomass, Molecular footprint polymers, Biosensors, Microbiology, Bioresources
Our search domains
Skills

Current content

• Biotechnology • Biomimetics • Plant metabolism • Biolubricants • Biofuels • Antioxidants • Anticancer • Antimicrobials • Antifungals • Antibiotic resistance • Study of pathogenic host relationship mechanisms
Workforce

Current content

Nombre de chercheurs : 24
Nombre de doctorants :
Nombre de personnel d'appui à la recherche : 13
Effectif total : 37
Example(s) of projects

Current content

• FuturoLeaf: develops a bio-inspired SSCF technology based on the hierarchical and porous 3D assemblies of nanocellulosic materials capturing water and transporting gases and nutrients for the photosynthetic microbial cells 🡭 • SAMOSS: Improving the development of biosensors in combination with optochemical detection techniques in application areas and through wider dissemination of knowledge • EraDic: Develop a predictive tool for recurrence in patients with chronic myeloid leukemia after cessation of conventional treatment with first- and second-generation kinase inhibitors • COALA: elucidate the antifungal mode of action of amphiphilic lipid compounds on rapeseed pathogens. • XYLESA: isolate specific peptide ligands of lipase secreted in the establishment of diseases associated with Xylella fastidiosa, capable of recognizing it for diagnostic applications and inhibiting its enzymatic activity for phytosanitary applications. • ANOI aims to determine the identification and classification of oilseed plants of interest and to improve the productivity of oilseed crops of four model plants.
Example(s) of publications

Current content

1. Raquel Martins-Noguerol, Sebastien Acket, Manuel Adrián Troncoso-Ponce, Rafael Garcés, Mónica Venegas-Calerón et al. Characterization and impact of sunflower plastidial octanoyltransferases (Helianthus annuus L.) on oil composition Journal of Plant Physiology, Elsevier, 2022, 274, pp.153730. 🡭 2. Sivanandam Veeramuthu Natarajan, Nicola D’amelio, Victor Muñoz. NMR Relaxation Dispersion Methods for the Structural and Dynamic Analysis of Quickly Interconverting, Low-Populated Conformational Substates Protein Folding, 2376, Springer US, pp.187-203, 2022, Methods in Molecular Biology, 🡭 3.Thomas Verissimo, Anna Faivre, Anna Rinaldi, Maja Lindenmeyer, Vasiliki Delitsikou et al. Decreased Renal Gluconeogenesis Is a Hallmark of Chronic Kidney Disease Journal of the American Society of Nephrology, American Society of Nephrology, 2022, 🡭 4. Juan Carlos Rubio-Gutierrez, Pablo Mendez-Hernández, yann Guéguen, Pierre Galichon, Marcela Tamayo-Ortiz et al. Overview of Traditional and Environmental Factors Related to Bone Health Environmental Science and Pollution Research, Springer Verlag. 🡭 5. Nébéwia Griffete, Laurent Michot, Carlo Gonzato. An easy synthesis of small, stable and water-compatible superparamagnetic protein-specific molecularly imprinted nanoparticles Polymer, Elsevier, 2022, 239, pp.124446. 🡭 All our publications can be found here : 🡭
Collaborations/Partners/Scientific clients

Current content

Université Picardie Jules Verne, Sorbonne Université, INSERM, Université de Paris, Université de Reims Champagne-Ardenne, Institut Pasteur, Russian Academy Of Scinces, Université de Lille, Université de Laval, VTT Technical Research Centre of Finland Ltd
Collaborations/Partners/Private Clients

Current content

EXTRACTIS, SAS PIVERT, SAS IMPROVE, OLEON, SANOFI, L'OREAL
Services offers
Training offers

Current content

We provide training on all our skills
Services offers

Current content

We provide services on all our skills
Consulting services

Current content

We provide consulting services on all our skills
Equipments
Equipements spécifiques

Current content

  • UV-VIS spectrometers
    Cary 60 and Specord 205/ Agilent et AnalytiK Jena
  • Fluorescence spectrometers
    Fluorolog, Cary Eclipse et Fluorescence polarization plate reader/ Horriba, Varian et BMG
  • GEC - Zetasizer Nano ZS Nanometer Instrument
    Zetasizer Nano ZS/ Malvern
  • Nanoparticle Tracking Analysis
    Malvern
  • GEC - Confocal Raman Spectrometer
    Alpha 300R/ WITec
  • NMR spectrometer, Bruker Avance III 400, BBFO probehead
    Avance III 400/ Bruker
  • Nicolet iS50 FTIR Spectrometer
Ecosystem
Affiliated institutions / organisations

Current content

  • University of Picardie Jules Verne (UPJV)
  • CNRS
  • Université de Technologie de Compiègne (UTC)
Établissement(s) partenaire(s)

Current content

Unit(s) of attachment

Current content

Groups/Networks/Federations

Current content

Doctoral schools

Current content

Equipex/EquipEx+/ESR

Current content

Competitive cluster

Current content

Regional strategic areas of activity

Current content

  • Chemistry and Materials
  • Bioeconomy
  • Industrial processes engineering, efficient processes
  • Biobased chemistry
  • Textiles, composites, materials
  • Recycling of materials and efficient use of material resources
  • Processes applied to the bioeconomy
Personal informations
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