• Health and Nutrition

Cellular Adiposity and Bone (MABLAB)

Research unit - ULR 4490

Description

Our unit brings together clinical researchers (rheumatologists, orthopedic surgeons, dental surgeons, radiologists) and non-clinicians (physiologists, cellular and molecular biologists, biochemists, spectrometrists) Their skills converge on the study of the relationships between bones and fatty tissues and their consequences on the pathophysiology of bone diseases. Our scientific project is based on the hypothesis that intra-bone changes play an important role in the pathophysiology of osteoporosis and osteonecrosis. These alterations correspond to a change in the distribution of the different components of bone tissue and involve interactions between osteogenesis and adipogenesis. Based on the clinical skills of the members of the laboratory, three pathologies are specifically studied: osteoporosis, osteonecrosis of the femoral head, osteonecrosis of the maxilla.

Contacts

Informations

Faculté de Chirurgie Dentaire, Place de Verdun
Université de Lille, Campus Santé
59000 LILLE

https://pmoi.univ-littoral.fr/

Effectif

Effectif total : 35

Personnel de recherche : 35

Expertises

Skills

• Osteogenesis and Adipogenesis
• Bone disease pathophysiology
• Bone pathology (post-menopausal osteoporosis, femoral head osteonecrosis, maxillary osteonecrosis, osteoarthritis)
• Role of bone marrow adipocyte in bone pathology

Collaborations/Partners/Scientific clients

Several national and international collaborations:

National:
Sorbonne, Jean Monnet University

International:
KU Leuven (Belgium), University of Edinburgh (United Kingdom), Erasmus University Rotterdam (Netherlands),

Services offers

Applications sectors

  • Science / Research

Services provided

We do not currently have any services to offer you.

Equipments

Nous disposons :
- Microspectromètres Raman
- microCT haute résolution

Ecosystem

Affiliated institutions / organisations

CHU de Lille
University of Lille
Université du Littoral Côte d'Opale (ULCO)

Doctoral schools

Regional strategic areas of activity

  • Health and Nutrition

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Thematics

Current thematics

  • Health and Nutrition
Title

Current content

Cellular Adiposity and Bone
Type

Current content

Research unit
Description

Current content

Our unit brings together clinical researchers (rheumatologists, orthopedic surgeons, dental surgeons, radiologists) and non-clinicians (physiologists, cellular and molecular biologists, biochemists, spectrometrists) Their skills converge on the study of the relationships between bones and fatty tissues and their consequences on the pathophysiology of bone diseases. Our scientific project is based on the hypothesis that intra-bone changes play an important role in the pathophysiology of osteoporosis and osteonecrosis. These alterations correspond to a change in the distribution of the different components of bone tissue and involve interactions between osteogenesis and adipogenesis. Based on the clinical skills of the members of the laboratory, three pathologies are specifically studied: osteoporosis, osteonecrosis of the femoral head, osteonecrosis of the maxilla.
Contact informations
Contact

Current content

URL

Current content

https://pmoi.univ-littoral.fr/

Address

Current content

Faculté de Chirurgie Dentaire, Place de Verdun
Université de Lille, Campus Santé
59000 LILLE
Keywords

Current content

Bone physiology, Bone pathophysiology, Bone diseases, Bone marrow adipose tissue, Bone marrow adiposity, Osteoporosis, Osteonecrosis, Inflammation, Osteoarthritis, Adipogenesis
Our search domains
Skills

Current content

• Osteogenesis and Adipogenesis • Bone disease pathophysiology • Bone pathology (post-menopausal osteoporosis, femoral head osteonecrosis, maxillary osteonecrosis, osteoarthritis) • Role of bone marrow adipocyte in bone pathology
Workforce

Current content

Nombre de chercheurs : 35
Nombre de doctorants :
Nombre de personnel d'appui à la recherche :
Effectif total : 35
Example(s) of projects

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Example(s) of publications

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Collaborations/Partners/Scientific clients

Current content

Several national and international collaborations: National: Sorbonne, Jean Monnet University International: KU Leuven (Belgium), University of Edinburgh (United Kingdom), Erasmus University Rotterdam (Netherlands),
Collaborations/Partners/Private Clients

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Services offers
Training offers

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Services offers

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We do not currently have any services to offer you.
Consulting services

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Equipments
Equipements spécifiques

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  • MABLAB - Raman microspectrometer
    OMARS 89/ Horiba Jobin Yvon
  • Raman microspectrometer
    LabRAM HR/ Horiba Jobin Yvon
  • MABLAB - X-ray microtomograph
    Skyscan 1172/ Brucker
Ecosystem
Affiliated institutions / organisations

Current content

  • CHU de Lille
  • University of Lille
  • Université du Littoral Côte d'Opale (ULCO)
Établissement(s) partenaire(s)

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Unit(s) of attachment

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Groups/Networks/Federations

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Doctoral schools

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Equipex/EquipEx+/ESR

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Competitive cluster

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Regional strategic areas of activity

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  • Health and Nutrition
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