• Bioeconomy
  • Chemistry and Materials
  • Digital World and Robotics
  • Health and Nutrition
  • Societal and economic transition & Risk management

Cell Engineering and Protein Analysis (ICAP)

Platform

Description

ICAP is the Cell Engineering and Protein Analysis Platform of the University of Picardie Jules Verne. It is located within the Centre Universitaire de Recherche en Santé (CURS) within the University Hospital of Amiens. It is open to the private and public sectors without any thematic, institutional or geographical conditions. The support offered by ICAP consists in the provision of advanced instruments for cell imaging and protein analysis to research teams, as well as support, scientific and technical assistance and, if necessary, user training. The staff ensures the maintenance, the evolution, by a constant technological watch.

The ICAP platform is part of the Institut de Chimie de Picardie FR CNRS 3085, which has been certified by the Ministry of Research and the CNRS as part of the latest HCERES wave.

Contacts

  • Paulo MARCELO
    Director
  • Alexandra BAYLE
    Secretary

Informations

Centre Universitaire de Recherche en Santé (CURS)
CHU Sud - Avenue Laënnec
80054 Amiens cedex 1

https://icap.u-picardie.fr/

Cell Engineering and Protein Analysis

Chiffres clés

Every year: 10 academic projects, 4 industrial projects, a few thousand analyses in total

Expertises

Skills

1. Mass spectrometry:
• Molecule analyses (peptides, proteins, metabolites), identification, exact mass, structural elucidation.

• Proteomics analyses, differential quantification (TMT, Label free, ...).

• Assays of molecules (peptides, metabolites, pesticides, ...) using MRM approaches.

• Metabolomic analyses.

2. Cell Imaging
• Flow cytometry: - Measurement and quantification of fluorescence of a large number of high-speed particles on different organelles; - Studies of physiological phenomena: cell cycle, apoptosis, ionic flux...

• Confocal microscopy: - Specific in situ localization of one or more fluorescent probes; - Acquisition of series of optical sections allowing 3D reconstruction; - Physiological studies with 4D study possibilities.

• Light-leaf microscopy: - Making optical slices of a large sample; - Acquisition of series of optical sections allowing 3D reconstruction; - Physiological studies with 4D study possibilities.

• Laser microdissection: - Isolation, under morphological control, of cells or groups of cells to perform genomic and/or proteomic studies using a UV laser beam.

3. Small animal imaging:
• Imaging: - Detection, localization, quantification of optical signal in bioluminescence and fluorescence in a dynamic and non-invasive manner.

• X-ray microtomography: X-ray imaging that allows you to visualize the internal structure of objects and organs in a dynamic and non-invasive way.

Example(s) of projects

Study of the impact of the use of natural defense stimulators (SDN) on the wall in rapeseed through a differential proteomic approach: 🡭

ANR JCJC: 🡭

Collaborations/Partners/Scientific clients

National: UPJV research teams, CHU Amiens, Dijon, Tours, Lille, Caen, University of Rouen, Reims, Lille, Tours, Sorbonne, Paris-Saclay, IPMC, Agro-Paris Tech, UTC Compiègne, Institut Faire Face.

International: Annaba University, University of Beirut, HITS, USTH, UAEM, Biotechnology Center of Borj Cedria

Collaborations/Partners/Private Clients

SATT NORD, Sanofi, Stolz, Lallemand, Zeiss, Waters, Thermo Electron Veolia, Tereos, Ingredia, Linéa, Improve, Urgo, Adocia, Veolia, Laboratoires Brothier, ISVV, Linea, Soufflet Technologies,

Services offers

Applications sectors

  • Biotechnology
  • Health / wellness
  • Science / Research

Services provided

We provide services according to our skills

Consulting services

We provide consulting services on all our skills

Equipments

You can find the detailed equipment list here : 🡭

Equipments

Nom Modèle Marque
Confocal microscope LSM780 / Zeiss
Light sheet microscope LighSheet Z1 / Zeiss
Laser Microdissector Palm Beam/ Zeiss
Flow cytometer FACS Canto II / BD Biosciences
Mass spectrometer Orbitrap XL / Thermo Fischer Scientific
Mass spectrometer Orbitrap FUSION / Thermo Fischer Scientific
Mass spectrometer XEVO-TQS / Waters
Solid phase extraction robot APEC GW-241 / Gilson
High Performance Liquid Chromatography U3000 micro-débits / Thermo Fischer Scientific
High Performance Liquid Chromatography U3000 nano-débits / Thermo Fischer Scientific
High Performance Liquid Chromatography H-Class microdébits / Waters
Pipetting robot EVO 150 / Tecan
X-ray microtomograph Skuscan 1176 / Bruker
Multiplexing analysis apparatus MagPix / Merck Millipore
Photon Imager Small Animal Imaging Station Photon Imager / Biospace Lab
2D Gel System Protean i12 IEF / Bio-rad
Bead mill MM400 / Retsch

Ecosystem

Affiliated institutions / organisations

University of Picardie Jules Verne

Partner institution(s)

L’Institut de Chimie de Picardie (ICP)

Regional strategic areas of activity

  • Bioeconomy
    • Animal feed - feed
    • Biobased chemistry
    • Biobased materials
    • Sustainable production and mobilization of bioresources
  • Chemistry and Materials
    • Green chemistry
  • Digital World and Robotics
    • Artificial intelligence, image processing, data science
  • Health and Nutrition
    • Food ingredients
    • Genetics, biomarkers and biomolecules
    • Medicine of the future: new health equipment and e-health
    • New therapeutic approaches
    • Prevention, well-being and the silver economy
    • Safe, healthy and sustainable food
  • Societal and economic transition & Risk management
    • Resilience, risk factors and fragility

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Thematics

Current thematics

  • Bioeconomy
    • Animal feed - feed
    • Biobased chemistry
    • Biobased materials
    • Sustainable production and mobilization of bioresources
  • Chemistry and Materials
    • Green chemistry
  • Digital World and Robotics
    • Artificial intelligence, image processing, data science
  • Health and Nutrition
    • Food ingredients
    • Genetics, biomarkers and biomolecules
    • Medicine of the future: new health equipment and e-health
    • New therapeutic approaches
    • Prevention, well-being and the silver economy
    • Safe, healthy and sustainable food
  • Societal and economic transition & Risk management
    • Resilience, risk factors and fragility
Title

Current content

Cell Engineering and Protein Analysis
Type

Current content

Plateforme analytique
Description

Current content

ICAP is the Cell Engineering and Protein Analysis Platform of the University of Picardie Jules Verne. It is located within the Centre Universitaire de Recherche en Santé (CURS) within the University Hospital of Amiens. It is open to the private and public sectors without any thematic, institutional or geographical conditions. The support offered by ICAP consists in the provision of advanced instruments for cell imaging and protein analysis to research teams, as well as support, scientific and technical assistance and, if necessary, user training. The staff ensures the maintenance, the evolution, by a constant technological watch.

The ICAP platform is part of the Institut de Chimie de Picardie FR CNRS 3085, which has been certified by the Ministry of Research and the CNRS as part of the latest HCERES wave.
Contact informations
Contact

Current content

Contact name Email phone number
MARCELO Paulo paulo.marcelo@u-picardie.fr 03 22 82 54 32
BAYLE Alexandra alexandra.bayle@u-picardie.fr 03 22 82 54 36
URL

Current content

https://icap.u-picardie.fr/

Address

Current content

Centre Universitaire de Recherche en Santé (CURS)
CHU Sud - Avenue Laënnec
80054 Amiens cedex 1
Keywords

Current content

Mass Spectrometry, Cell Imaging, X-ray Microtomography, Proteomic Analysis, Metabolomic Analysis, Metabolites, Flow Cytometry, Confocal Microscopy, Laser Microdissection, Light Leaf Microscopy
Our search domains
Skills

Current content

1. Mass spectrometry: • Molecule analyses (peptides, proteins, metabolites), identification, exact mass, structural elucidation. • Proteomics analyses, differential quantification (TMT, Label free, ...). • Assays of molecules (peptides, metabolites, pesticides, ...) using MRM approaches. • Metabolomic analyses. 2. Cell Imaging • Flow cytometry: - Measurement and quantification of fluorescence of a large number of high-speed particles on different organelles; - Studies of physiological phenomena: cell cycle, apoptosis, ionic flux... • Confocal microscopy: - Specific in situ localization of one or more fluorescent probes; - Acquisition of series of optical sections allowing 3D reconstruction; - Physiological studies with 4D study possibilities. • Light-leaf microscopy: - Making optical slices of a large sample; - Acquisition of series of optical sections allowing 3D reconstruction; - Physiological studies with 4D study possibilities. • Laser microdissection: - Isolation, under morphological control, of cells or groups of cells to perform genomic and/or proteomic studies using a UV laser beam. 3. Small animal imaging: • Imaging: - Detection, localization, quantification of optical signal in bioluminescence and fluorescence in a dynamic and non-invasive manner. • X-ray microtomography: X-ray imaging that allows you to visualize the internal structure of objects and organs in a dynamic and non-invasive way.
Key data

Current content

Every year: 10 academic projects, 4 industrial projects, a few thousand analyses in total
Workforce

Current content

Effectif total :
Example(s) of projects

Current content

Study of the impact of the use of natural defense stimulators (SDN) on the wall in rapeseed through a differential proteomic approach: 🡭 ANR JCJC: 🡭
Example(s) of publications

Current content

Collaborations/Partners/Scientific clients

Current content

National: UPJV research teams, CHU Amiens, Dijon, Tours, Lille, Caen, University of Rouen, Reims, Lille, Tours, Sorbonne, Paris-Saclay, IPMC, Agro-Paris Tech, UTC Compiègne, Institut Faire Face. International: Annaba University, University of Beirut, HITS, USTH, UAEM, Biotechnology Center of Borj Cedria
Collaborations/Partners/Private Clients

Current content

SATT NORD, Sanofi, Stolz, Lallemand, Zeiss, Waters, Thermo Electron Veolia, Tereos, Ingredia, Linéa, Improve, Urgo, Adocia, Veolia, Laboratoires Brothier, ISVV, Linea, Soufflet Technologies,
Services offers
Training offers

Current content

Services offers

Current content

We provide services according to our skills
Consulting services

Current content

We provide consulting services on all our skills
Equipments
Equipements spécifiques

Current content

  • Confocal microscope
    LSM780 / Zeiss
  • Light sheet microscope
    LighSheet Z1 / Zeiss
  • Laser Microdissector
    Palm Beam/ Zeiss
  • Flow cytometer
    FACS Canto II / BD Biosciences
  • Mass spectrometer
    Orbitrap XL / Thermo Fischer Scientific
  • Mass spectrometer
    Orbitrap FUSION / Thermo Fischer Scientific
  • Mass spectrometer
    XEVO-TQS / Waters
  • Solid phase extraction robot
    APEC GW-241 / Gilson
  • High Performance Liquid Chromatography
    U3000 micro-débits / Thermo Fischer Scientific
  • High Performance Liquid Chromatography
    U3000 nano-débits / Thermo Fischer Scientific
  • High Performance Liquid Chromatography
    H-Class microdébits / Waters
  • Pipetting robot
    EVO 150 / Tecan
  • X-ray microtomograph
    Skuscan 1176 / Bruker
  • Multiplexing analysis apparatus
    MagPix / Merck Millipore
  • Photon Imager Small Animal Imaging Station
    Photon Imager / Biospace Lab
  • 2D Gel System
    Protean i12 IEF / Bio-rad
  • Bead mill
    MM400 / Retsch
Ecosystem
Affiliated institutions / organisations

Current content

  • University of Picardie Jules Verne
Établissement(s) partenaire(s)

Current content

L’Institut de Chimie de Picardie (ICP)
Unit(s) of attachment

Current content

Groups/Networks/Federations

Current content

Competitive cluster

Current content

Regional strategic areas of activity

Current content

  • Health and Nutrition
  • Safe, healthy and sustainable food
  • Chemistry and Materials
  • Green chemistry
  • Bioeconomy
  • Genetics, biomarkers and biomolecules
  • Food ingredients
  • Biobased chemistry
  • New therapeutic approaches
  • Societal and economic transition & Risk management
  • Resilience, risk factors and fragility
  • Prevention, well-being and the silver economy
  • Sustainable production and mobilization of bioresources
  • Digital World and Robotics
  • Artificial intelligence, image processing, data science
  • Medicine of the future: new health equipment and e-health
  • Biobased materials
  • Animal feed - feed
Labelling

Current content

Personal informations
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