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Health and Nutrition
BioImaging Center Lille (BICeL)
Platform
Our platform is dedicated to cellular, tissue and small animal imaging (rodent and aquatic models). Our services are structured around five technological platforms: electron microscopy, photonic microscopy, cytometry and flow imaging. We possess a wide range of innovative equipment and support research activities of more than 400 researchers and 112 national and international research teams. We are open to all academic and industrial collaborations and propose services and training in line with our expertise.
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Nathalie Jouy
Technical manager -
Frank Lafont
Research director -
Sophie Salomé-Desnoulez
Technical manager -
Meryem Tardivel
Technical manager
1 rue du professeur Calmette
59019 LILLE
https://ums-plbs.univ-lille.fr/les-plateformes-constitutives/imagerie-cellulaire
Chiffres clés
• >250 users/year• >16 publications/year
• 232 projects / year including 7% industrial projects
• 84 publications over the period 2015-2019
Skills
• Light microscopy (FRAP, FRET, FLIM, SIM) in a containment environment
• Conventional and spectral cytometry, flow imaging and cell sorting, including in a containment environment
• Preparation of samples
• Data analysis and interpretation
• Image analysis
• High resolution cellular, tissue and intravital imaging of small animals
Collaborations/Partners/Scientific clients
Université de Rouen, Institut Curie, Institut Pasteur Paris, Institut Cochin, Université de Technologie de Compiègne, Université de Toulouse, Sorbonne Université, ANSES
International:
Weizmann Institute of Science (Israel), Université Libre de Bruxelles (Belgium)
Applications sectors
- Biotechnology
- Health / wellness
- Science / Research
Services provided
• Transmission electron imaging (TEM) and scanning electron imaging (SEM), including (cryo)tomography
• Assistance in the preparation of samples and the choice of the appropriate system for the scientific problem
• Assistance in the design, acquisition and analysis of data
• Support for all or part of a study project (preparation, immuno-staining, acquisition, data analysis) as part of the service provision
• Services in image restoration by 3D deconvolution
Training offers
• Theoretical bases of cytometry
• Practice in cytometry
• Practice in electron microscopy
• Theory and practice in light microscopy
• Image analysis
• Videomicroscopy
• Transparency and 3D imaging
Consulting services
• electron microscopes
• high content microscopes
• Photonic microscopes (confocal, PALM, TIRF, PALM-SIM, multiphoton, video microscopes, epifluorescence microscopes, light sheet microscopes, slide scanner)
• flow cytometers
• ultramicrotomes and cryo-ultramicrotomes
• cryo-fixation and cruo-substitution devices
See the detailed list of equipment: https://www.ibisa.net/plateformes/bioimaging-center-lille-bicel-241.html
Equipments
| Nom | Modèle | Marque |
|---|---|---|
| Ultramicrotome | Ultracut R/ | Leica |
| Transmission electron microscopy (TEM) | JEM 2100/ | JEOL |
| Transmission electron microscopy (TEM) | H7500/ | Hitachi |
| Scanning electron microscope (SEM) | Merlin Compact VP/ | Zeiss |
| Confocal microscope | LSM 780 fast Airy scan/ | Zeiss |
| Flow cytometer | LSR Fortessa X20/ | BD |
| Light sheet fluorescence microscopy (LSFM) | Ultramicroscope/ | Lavision |
| Fast video microscope | SD live SR/ | Nikon Roper |
| Multimodal FLIM microscope | A1/ | Nikon |
| Two-photon excitation microscopy | SP8/ | Leica |
Affiliated institutions / organisations
Unit(s) of attachment
Groups/Networks/Federations
Labellisations
Regional strategic areas of activity
- Health and Nutrition
- Food ingredients