• Chemistry and Materials
  • Health and Nutrition

SMART Mass Spectrometry and Proteomics (SMART)

Platform

Description


Our SMART technical platform offers services to carry out projects related to the identification and quantification of small pharmaceutical molecules or drugs. We also identify proteins on a large scale through proteomic studies, their quantification and separation, or through the search for biomarkers of clinical biological samples. We also carry out quality control of chemical synthesis molecules by mass spectrometry. Recently, we have developed a new theme which consists in lipidomic analysis of cellular or biological samples (serum, CSF...). Integrated in the Laboratory of the Blood-Brain Barrier of the University of Artois (UR2465), we quantify the passage of molecules through the BHE by mass spectrometry.
We are open to all academic and industrial collaborations and offer training and services related to our expertise.

Contacts

  • Sophie Duban-Deweer
    Scientific manager

Informations

Rue Jean Souvraz - SP18
62307 LENS

http://lbhe.univ-artois.fr/plateforme-de-spectrometrie-de-masse

Chiffres clés

• Number of projects per year: 5
• Other Key Figures: 300 chemical runs / year, 100 proteomics runs/year

Effectif

Effectif total : 3

Expertises

Skills

• Mass spectrometry
• Chromatography
• Proteomics
• Lipidomic
• Chemical Analysis Mass Spectrometry
• MALDI and ESI ionization

Example(s) of projects

• Participate in a prenatal diagnostic test for sickle cell disease using 🡭
• Search for a biomarker for colon cancer, which led to the creation of a diagnostic test (partnership with Oncodiag)
• Qualitative analysis of protein contained in patient cell secretome 🡭
• Measure the passage of molecules through the BHE 🡭

Collaborations/Partners/Scientific clients

Nationales : Université de Lille, Université d'Artois, UCCS, INSERM, Université du Maine, Institut Cochin, Hôpital H. Mondor

Internationales : Université de Mons (Belgique), Université de Lisbonne (Portugal)

Collaborations/Partners/Private Clients

Genfit, Gènes Diffusion, Oncodiag

Services offers

Applications sectors

  • Biotechnology
  • Agriculture
  • Education / Training
  • Chemistry / Plastics (Glue, Plastic, Rubber...)
  • Science / Research

Services provided

The technical platform covers several types of services, such as direct access to instruments, the performance of analyses via services, and larger research collaborations or contracts. Example of services:
• Identification by MS or MS/MS,
• Complex mixture analysis (cell culture, serum, CSF, plasma, chemical synthesis mixture),
• Identification of chemical compounds,
• Trace analysis

Training offers

MALDI or ESI mass spectrometry, proteomic analysis methodology

Consulting services

We provide consulting services on all our skills

Equipments

Mass Spectrometry
MALDI-TOF/TOF UltraFlex II (Bruker Daltonics)
TripleTOF 5600+ MS

Other Equipment
Ekspert nanoLC 425 Eksigent
Thermo Ultimate ™ 3000 NanoLC
Selexion™ device for lipidomics
Gel Imaging and Quantification Analysis Tools 1D Band / Spots (Samespots ™)
2D Gel Electrophoresis Devices, SDS PAGE

Bioinformatics: MS-protein ProteinPilot advanced identification software; Mascot software, Analyst software, MultiQuant, Lipidview

Discover the detailed equipment list: here

Equipments

Nom Modèle Marque
MALDI-TOF/TOF ULTRAFLEX II/ Bruker Daltonics
Triple TOF 5600+/ Sciex
Selexion 5600+/ Sciex
Chromatograph U3000/ ThermoFisher Scientific
Chromatograph Ekspert nanoLC 425/ Sciex/ Eksigent

Ecosystem

Affiliated institutions / organisations

Artois University

Unit(s) of attachment

Competitive cluster

Regional strategic areas of activity

  • Chemistry and Materials
    • Organic chemistry
  • Health and Nutrition
    • Food ingredients
    • Genetics, biomarkers and biomolecules
    • New therapeutic approaches

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Thematics

Current thematics

  • Chemistry and Materials
    • Organic chemistry
  • Health and Nutrition
    • Food ingredients
    • Genetics, biomarkers and biomolecules
    • New therapeutic approaches
Title

Current content

SMART Mass Spectrometry and Proteomics
Type

Current content

Plateforme analytique
Description

Current content


Our SMART technical platform offers services to carry out projects related to the identification and quantification of small pharmaceutical molecules or drugs. We also identify proteins on a large scale through proteomic studies, their quantification and separation, or through the search for biomarkers of clinical biological samples. We also carry out quality control of chemical synthesis molecules by mass spectrometry. Recently, we have developed a new theme which consists in lipidomic analysis of cellular or biological samples (serum, CSF...). Integrated in the Laboratory of the Blood-Brain Barrier of the University of Artois (UR2465), we quantify the passage of molecules through the BHE by mass spectrometry.
We are open to all academic and industrial collaborations and offer training and services related to our expertise.
Contact informations
Contact

Current content

Contact name Email phone number
DUBAN-DEWEER Sophie sophie.duban@univ-artois.fr
URL

Current content

http://lbhe.univ-artois.fr/plateforme-de-spectrometrie-de-masse

Address

Current content

Rue Jean Souvraz - SP18

62307 LENS
Keywords

Current content

Proteomics, Mass spectrometry, Chromatography, MALDI, Triple-TOF, Pharmaceutical molecules, Lipidomics, Polymers, ESI, Quantification
Our search domains
Skills

Current content

• Mass spectrometry • Chromatography • Proteomics • Lipidomic • Chemical Analysis Mass Spectrometry • MALDI and ESI ionization
Key data

Current content

• Number of projects per year: 5 • Other Key Figures: 300 chemical runs / year, 100 proteomics runs/year
Workforce

Current content

Effectif total : 3
Example(s) of projects

Current content

• Participate in a prenatal diagnostic test for sickle cell disease using 🡭 • Search for a biomarker for colon cancer, which led to the creation of a diagnostic test (partnership with Oncodiag) • Qualitative analysis of protein contained in patient cell secretome 🡭 • Measure the passage of molecules through the BHE 🡭
Example(s) of publications

Current content

Collaborations/Partners/Scientific clients

Current content

Nationales : Université de Lille, Université d'Artois, UCCS, INSERM, Université du Maine, Institut Cochin, Hôpital H. Mondor Internationales : Université de Mons (Belgique), Université de Lisbonne (Portugal)
Collaborations/Partners/Private Clients

Current content

Genfit, Gènes Diffusion, Oncodiag
Services offers
Training offers

Current content

MALDI or ESI mass spectrometry, proteomic analysis methodology
Services offers

Current content

The technical platform covers several types of services, such as direct access to instruments, the performance of analyses via services, and larger research collaborations or contracts. Example of services: • Identification by MS or MS/MS, • Complex mixture analysis (cell culture, serum, CSF, plasma, chemical synthesis mixture), • Identification of chemical compounds, • Trace analysis
Consulting services

Current content

We provide consulting services on all our skills
Equipments
Equipements spécifiques

Current content

  • MALDI-TOF/TOF
    ULTRAFLEX II/ Bruker Daltonics
  • Triple TOF
    5600+/ Sciex
  • Selexion
    5600+/ Sciex
  • Chromatograph
    U3000/ ThermoFisher Scientific
  • Chromatograph
    Ekspert nanoLC 425/ Sciex/ Eksigent
Ecosystem
Affiliated institutions / organisations

Current content

  • Artois University
Établissement(s) partenaire(s)

Current content

Unit(s) of attachment

Current content

  • Blood-Brain Barrier Laboratory
Groups/Networks/Federations

Current content

Competitive cluster

Current content

Regional strategic areas of activity

Current content

  • Health and Nutrition
  • Chemistry and Materials
  • Genetics, biomarkers and biomolecules
  • Food ingredients
  • New therapeutic approaches
  • Organic chemistry
Labelling

Current content

Personal informations
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